The star has given the full amount of his £25k Mercury Prize cash to the trust for venues, which operates to preserve the UK's grassroots live music spots.
He was presented with the award on mid-October as his new release People Watching was declared the top album of the past year.
Fender has opted to give the cash to the Music Venues Trust, in appreciation of the vital role local spots fulfilled in his early career.
"As an artist couldn't be pursuing this success if it hadn't been for all the gigs I performed around the region, and elsewhere, when I was starting out," said Sam Fender. "These spaces are iconic, but they are in difficulty."
Beginning in 2023, at least 150 of these venues have permanently closed – about one-sixth of the entire UK sector.
Recently, top acts such as the band Pulp, the group Coldplay, the singer Katy Perry and Ed Sheeran have all aided the trust in its initiatives to keep the scene afloat, by applying a modest fee to their ticket prices, which goes to help local stages.
Fender also participated, collecting more than £100,000 on his recent tour to help numerous small stages across the UK.
The money supported locations that were facing imminent closure due to issues arising from flooding, fires and personal losses, as well as permit problems, court cases and sound issues.
Some locations received monetary aid in modernizing facilities and gear that helped artists and audiences.
"The concept that money from performances in major spaces backs the smaller venues, where it begins for artists like me, is just common sense," Fender has said.
Fender is among several artists to contribute his Mercury Prize funds to charitable organizations.
Back when they won the prize in the mid-90s for their record their work, frontman Cocker stated that the band would donate their winnings to the charity War Child.
In 2002, artist she split her bounty among multiple organizations, like the NSPCC and a charity for Sickle Cell.
"Additionally, I donated a £1,000 to Highgate Newtown, to their gymnastics class, because I practiced gymnastics when I was a child and they lacked updated gear," Ms Dynamite shared with outlets.
Two years ago, Ezra Collective contributed their funds to the community center that nurtured their act, alongside other grassroots music organisations.
And 1994 winners they donated their prize to a multiple sclerosis charity after a acquaintance was found to have the disease.
"The victory was sufficient," said vocalist the singer. "The cash was the extra but we didn't require the bonus, because we had the main prize. So our victory touched another person's life."
Last week, the trust announced it had rescued several grassroots venues in south-east England, by transferring them to community ownership.
The Joiners in that area and the second in the city were bought under the community ownership scheme, which is backed by Arts Council England and music fans who buy "ownership units" in the buildings.
